per·turb
[per-turb]
verb (used with object)
1. to disturb or disquiet greatly in mind; agitate.
2. to throw into great disorder; derange.
3. Astronomy . to cause perturbation  in the orbit of (a celestial body).
Synonyms 
1.   trouble. 2.  confuse, addle, muddle. 
Antonyms 
1.  pacify.